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On July 9, 2002 after reviewing over 100 studies the Federal Drug Administration (FDA) approved the general use of Neotame. These studies focused on absorption, distribution, metabolism, and excretion in mice, rats, dogs, rabbits, and humans. In humans it was found that 20 - 30% of the administered dose of Neotame is absorbed and rapidly de-esterfied to De-esterfied Neotame (the major metabolite of Neotame, Figure 2) which is then excreted in the urine and feces. The rest of Neotame is unchanged and also rapidly eliminated through the feces and urine and does not accumulate in the body. Findings also concluded that:
Even though Neotame has been approved, not only in the United States, but also in Australia, China, and New Zealand, long term affects are as of yet unknown. Also there are many websites and magazine articles out there that claim that Neotame is extremely bad for human consumption, however they do not give reasons or studies to support such claims. There are other health concerns which are related
to all artificial sweeteners, according to a SignOnSanDiego.com article,
is that people think that because most sweeteners are non-nutritive
they can eat twice to three times as much of the same foods. Also this
makes it so that people are more tempted to go for the cookie with the
non-nutritive sweetener than fruit which may carry the same amount of
calories but also contains good vitamins and fiber.
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website by Chris Demke last updated 19 Mar 2006 |