Sex-Linkage

I. Genes on Sex Chromosomes

• nomenclature
  • + = wild type

II. Sex-linkage in Drosphila

• Sex determination in Fruit Flies
• White eye gene
• Inheritance patterns of sex-linked genes
• Hemizygosity

III. Chromosome theory of Inheritance

• Bridge's work with the white eye gene
• Inheritance and cytology

IV. Sex-linkage in Humans

• Sex determination in Humans
  • Y chromosome
  • SRY region and the TDF gene
  • testosterone
  • Dihydroxytestosterone (DHT)
  • testicular feminization
• Hetero and homogametic sex
• Sex linked traits
  • color blindness
  • Muscular dystorphy
  • lesch-nyhan syndrome
  • hemophilia
• Y linked traits

V. Sex limited and Sex influenced traits