Organic Study Topics

DISCLAIMER: This is not an inclusive list of all potential topics that could be on the final.

You need to know all the functional groups and their names, properties, how they can be prepared and their reactions.

Here are some specific topics that are not to be missed.

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Nomenclature alkanes, alkenes, alkynes, benzene compounds, alcohols, aldehydes, ketones, carboxylic acids, acid chlorides, anhydrides, esters, amides, carboxylate salts, alkyl halides, amines, ethers

Intermolecular forces and how they relate to physical properties

Bonding, formal charge, hybridization, geometry, determining dipole moment in a compound

Acid and Base properties….pKa…..structural features which affect acidity and basicity…relative acidity of hydrogens in organic molecules….rank compound in order of increasing/decreasing acidity or basicity

Types of isomers…..E & Z; R & S: enantiomers, diastereomers, meso compounds, optical activity

Carbocations…stability (primary, secondary, tertiary, allylic, benzylic)….what they do…. especially rearrangements

Reaction Types….Sn1, Sn2, E1, E2, electrophilic aromatic substitution, free radical substitution, nucleophilic addition…..you need to be able complete reactions for all functional groups studied and understand the mechanism for those reaction classes listed above….be able to draw intermediates and transition states for reaction mechanisms…be able to place in relative reactivity a group of compounds for a given type of reaction…use a reaction coordinate diagram (potential energy diagram) for a particular reaction pathway

For Sn1/Sn2…..type of halides that react by each mechanism, stereochemistry, solvent effects.

Oxidation and Reduction Reactions….identifying organic oxidations and reduction…all the different oxidation and reducing agents and what groups they act on.

Aromatic compound….be able to determine if a compound is aromatic or not….directing effects/ ring activation or deactivation effects of substituents

Enolates…the different ways they act as nucleophiles

Identifying a compound from its NMR, C-13, IR or MS spectra

Some named reactions….Diels-Alder, Aldol, Grignard, Wittig, Claisen, Dieckmann